Description
Synonyms: Tetrazine-DPPE, DPPE Tetrazine, PE-Tetrazine, 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamide-Tetrazine
Tetrazine DPPE is a phospholipid conjugate containing a norbornene-functionalized head group covalently attached to 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE). The tetrazine moiety enables rapid and selective inverse electron-demand Diels–Alder (IEDDA) click reactions with alkene- and alkyne-functionalized molecules under mild, catalyst-free conditions.
The hydrophobic DPPE lipid readily incorporates into liposomes, lipid nanoparticles (LNPs), and cell membranes, while the exposed carbonylacrylic group provides a convenient handle for post-assembly surface modification. Tetrazine DPPE is widely used in targeted drug delivery, membrane labeling, biomaterials research, and diagnostic imaging applications.
Product Specifications:
- Form: Solid;
- Color: White;
- Lipid type: C16 saturated PE (Phosphoethanolamine);
- Purity: >98%;
Storage Conditions:
- Store at -20 °C; Protect from moisture and light.
